GTS-21 Dihydrochloride (DMBX-A)

Code: 5052770001 D2-231

Biochem/physiol Actions

Reversible: yes

Primary Targetα7 nAChR

General description

A partial agonist selective for α7 nAChRs (EC<...


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Biochem/physiol Actions

Reversible: yes

Primary Targetα7 nAChR

General description

A partial agonist selective for α7 nAChRs (EC50 = 10 µM). Used in neuroimmunology studies, cardiovascular disease research, and Alzheimer′s disease studies.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Kox, M., et al. 2011. Br. J. Anaesth.107, 559.Kox, M., et al., 2011. Shock.36, 5.Rosas-Ballina, M., et al. 2009. Mol. Med.15, 195.Briggs, A., et al. 1997. Pharmacol. Biochem. Behav.57, 231.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Warning

Toxicity: Standard Handling (A)

assay≥98% (HPLC)
coloryellow
formsolid
InChI keyBXKYFUGAAFLYJL-BXGYHSFXSA-N
InChI1S/C19H20N2O2.2ClH/c1-22-17-8-7-14(18(12-17)23-2)11-15-5-4-10-21-19(15)16-6-3-9-20-13-16;;/h3,6-9,11-13H,4-5,10H2,1-2H3;2*1H/b15-11+;;
manufacturer/tradenameCalbiochem®
Quality Level100
solubilityH2O: 100 mM, DMSO: 100 mM
storage conditionprotect from light, OK to freeze
storage temp.−20°C
Cas Number156223-05-1
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